Posted By: Dr. Gary Bellman on September 24, 2013
is a common condition seen through our practice– especially among older men, but often goes undiagnosed and untreated. It can be associated with a number of signs and symptoms that affect health
and quality of life
, including feelings of low energy
; decreased sex drive and performance; decreased muscle mass and strength; decreased bone mineral density; and increased body fat, particularly abdominal fat, a putative risk factor for metabolic syndrome and type 2 diabetes.
Numerous studies that have been carried out have established that insulin resistance is associated with low-grade inflammation. There is tremendous interest in the field on the role of chronic inflammation and the various biomarkers that probably are contributing to atherosclerosis (ASVD) and long-term cardiovascular disease. This is a hypothesis that testosterone-replacement therapy will benefit these markers and ultimately help aid with weight loss.
Normalizing serum testosterone
in obese hypogonadal
men reduced weight loss-waist circumference, blood pressure, and also marked reductions in fasting glucose; These improvements were progressive over the full 5 years of the study.
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